Demy works at the Erasmus Medical Center. In her project she aims to improve development and health by strengthening circadian rhythms early in life. Specifically, our objectives are to identify epigenetic health risk markers in preterm infants and establish a circadian rhythm assay as a predictor of later-life circadian performance. Additionally, she wants to elucidate the mechanisms underlying the effectiveness of intervention, by monitoring sleep, neurodevelopment and brain morphology.

More on Demy’s project.

Jorine works at the Erasmus Medical Center. In her project she aims to improve development and health by strengthening circadian rhythms early in life. Specifically, she will design a clinical intervention (e.g. maternal rhythm, feeding timing and composition, light conditions) that improves circadian development and postnatal growth and health.

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Emma works at the Eindhoven University of Technology on the restoration and optimization of the biological clock of mental healthcare patients with depression. Specifically she will optimize chronotherapeutic interventions to improve well-being and facilitate recovery in depressed patients. Additionally she will identify markers that predict response to antidepressant treatments and enable treatment selection

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Georgiana works at the Leiden University. In her project she aims to restore and optimize the biological clock of mental healthcare patients with depression. Specifically she wants to understand the brain mechanisms that make light therapy a successful antidepressant treatment. Also she will identify markers that predict response to antidepressant treatments and enable treatment selection. 

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Ward works at the Leiden University Medical Center. He wants to establish the role of the circadian clock in the response to cancer immunotherapy.

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Koen works at the RIVM and will investigate the timing of vaccinations. 

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Tamara works at the RIVM and will investigate the timing of vaccinations on the immune response.

More on Tamara’s project.

Inge works at the LACDR of the Leiden University. In her project she will look for new targets in the biological clock that will adjust the clock. This knowledge can be used to design new drugs and help restore a disrupted biological clock.

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Maitreyi aims to improve clock pharmacology by using library screening and developing translational clock assays using cultured brain tissue of murine models. Drug efficacy to boost clock function will thus be assessed at molecular, cellular and network levels.

More about Maitreyi’s project is coming soon.

Danielle works at the Institute for Biology in Leiden. She will study the mechanisms by which light pollution affects migrating fish, in order to identify strategies to preserve clock function.

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Hannah works at the University of Amsterdam. She contributes to the overall aim of this work package which is to quantify the temporal mismatching effects of light pollution in foodwebs, ranging from plants and herbivores to predators. Hannah works on insects and she will specifically aim to identify how different forms of light pollution lead to temporal (circadian) mismatches between plants, and the activity patterns of herbivores (insects). 

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Evelien works at the Leiden University. She studies the effects of light pollution on plants.

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Sander works at the Netherlands Institute of Ecology Wageningen. He studies the effects of nocturnal light exposure on bats.

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Gabriel works at the University of Groningen and NIOO in Wageningen. In his project he investigates many aspects of light and the effects it causes on phototaxis of animal species. 

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Maaike works at NIOO in Wageningen. The objective of her study is to see how light affects activity of behaviour of amphibians in time and space, and to see whether this effect changes under different intensities and spectral compositions of light.