{"id":4741,"date":"2022-03-11T16:05:20","date_gmt":"2022-03-11T16:05:20","guid":{"rendered":"https:\/\/bioclockconsortium.org\/?page_id=4741"},"modified":"2024-05-29T13:01:04","modified_gmt":"2024-05-29T13:01:04","slug":"ayano-shiba","status":"publish","type":"page","link":"https:\/\/bioclockconsortium.org\/en\/our-research\/early-career-researchers\/ayano-shiba\/","title":{"rendered":"Ayano Shiba"},"content":{"rendered":"<div>\n<p>Ayano Shiba<\/p>\n<\/div>\n<p><img decoding=\"async\" src=\"\/wp-content\/uploads\/2021\/09\/Ayano-Shiba-e1647002528375.jpeg\" alt=\"Image by Ayano Shiba\"><\/p>\n<ul>\n<li>\n<h3>About Ayano<\/h3>\n<div>\n<h6><strong>Workpackage <\/strong><\/h6>\n<p>1.2<\/p>\n<h6><strong>Position<\/strong><\/h6>\n<p>PhD<\/p>\n<h6><strong>Started<\/strong><\/h6>\n<p>September 2021<\/p>\n<h6><strong>Works at<\/strong><\/h6>\n<p>Netherlands Institute for Neuroscience<\/p>\n<h6><strong>Supervision Team<\/strong><\/h6>\n<ul>\n<li>Prof. Andries Kalsbeek<\/li>\n<li>Dr. Chun-Xia Yi<\/li>\n<li>Dr. Dirk-Jan Stenvers<\/li>\n<li>Dr. Joram Mul<\/li>\n<\/ul>\n<h6><strong>Email<\/strong><\/h6>\n<p><a href=\"\/a.shiba@nin.knaw.nl\">a.shiba@nin.knaw.nl<\/a><\/p>\n<\/p>\n<\/div>\n<\/li>\n<li>\n<h3>Description of project<\/h3>\n<div>\n<p>My project aims to clarify how timed exercise impact on the metabolic system, and possibly develop the prevention and treatment for circadian disruption-triggered metabolic diseases; obesity and type 2 diabetes mellitus.<\/p>\n<p>Currently we know that disturbance of the circadian clock triggered by shift work conditions are known to contribute to infertility, carcinogenesis and metabolic disorders. In the past years, a number of studies with rodents have reported on positive effects of forced exercise at specific times of day. Both circadian rhythms and metabolic effects were improved. However, the study of de Goede from our team strongly suggested that forced exercise protocols cause enormous activity of the stress system in the body. Therefore, our aim is to investigate the importance of timed exercises for the metabolic system without stress artifacts.<\/p>\n<p>Ultimately we want to develop prevention methods and treatments for metabolic disorders caused by disturbances of the biological clock.<\/p>\n<p><a href=\"https:\/\/bioclockconsortium.org\/en\/news\/the-first-researcher-introduces-herself\/\" target=\"_blank\" rel=\"noopener\">Read Ayano&#8217;s personal introduction here.<\/a><\/p>\n<p><strong>Year ONE<\/strong> (September &#8217;22): the first year of Ayano&#8217;s project has passed. She wrote <a href=\"https:\/\/bioclockconsortium.org\/en\/news\/a-one-year-update-ayano-on-the-timing-of-exercise\/\">an update<\/a> on what she has done so far.<\/p>\n<\/div>\n<\/li>\n<\/ul>\n<h2>KEEP UP TO DATE OF NEWS, NEW PROJECTS AND VACANCIES FROM BIOCLOCK CONSORTIUM<\/h2>\n<p><img decoding=\"async\" src=\"\/wp-content\/uploads\/2021\/03\/logo-bioclock-menu.png\" alt=\"Logo BioClock consortium\"><\/p>\n<h3>Contact<\/h3>\n<hr>\n<div>\n<p>BioClock Consortium<br \/><a href=\"\/bioclock@lumc.nl\">bioclock@lumc.nl<\/a><\/p>\n<\/div>\n<h3>Follow us<\/h3>\n<hr>\n<ul>\n<li>\n<p><a href=\"\/en\/news\/\"><\/p>\n<p>News<\/p>\n<p><\/a><\/p>\n<\/li>\n<li>\n<p><a href=\"https:\/\/twitter.com\/\"><\/p>\n<p><a href=\"https:\/\/twitter.com\/NWA_BioClock\">Twitter<\/a><\/p>\n<p><\/a><\/p>\n<\/li>\n<li>\n<p><a href=\"https:\/\/www.instagram.com\/\"><\/p>\n<p><a href=\"https:\/\/www.linkedin.com\/company\/bioclock\">LinkedIn<\/a><\/p>\n<p><\/a><\/p>\n<\/li>\n<\/ul>\n<p><img decoding=\"async\" src=\"\/wp-content\/uploads\/2021\/03\/NWO-logo-witruimte.png\" alt=\"NWO logo\"><\/p>\n<div>\n<p>The BioClock Consortium is funded by the NWA-ORC programme of the Dutch Research Council (NWO; project number 1292.19.077).<\/p>\n<\/div>\n<p><!--more--><br \/>\n<!-- {\"type\":\"layout\",\"children\":[{\"name\":\"header\",\"type\":\"section\",\"props\":{\"width\":\"default\",\"padding\":\"large\",\"style\":\"muted\",\"image_position\":\"center-right\",\"padding_remove_top\":false,\"animation\":\"fade\",\"image\":\"\",\"vertical_align\":\"middle\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"title_breakpoint\":\"xl\",\"media_visibility\":\"m\"},\"children\":[{\"name\":\"\",\"type\":\"row\",\"props\":{\"margin\":\"xlarge\"},\"children\":[{\"name\":\"\",\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"media_overlay_gradient\":\"\",\"width_medium\":\"1-1\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"name\":\"\",\"type\":\"headline\",\"props\":{\"title_element\":\"div\",\"content\":\"\n\n<p>Ayano Shiba<\\\/p>\",\"title_style\":\"heading-small\",\"text_align\":\"center\",\"maxwidth\":\"2xlarge\",\"margin\":\"large\",\"margin_remove_bottom\":true,\"block_align\":\"center\"}},{\"name\":\"\",\"type\":\"divider\",\"props\":{\"divider_element\":\"div\",\"divider_style\":\"small\",\"divider_align\":\"center\",\"margin\":\"medium\"}}]}]}]},{\"type\":\"section\",\"props\":{\"style\":\"default\",\"width\":\"default\",\"vertical_align\":\"middle\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"title_breakpoint\":\"xl\",\"image_position\":\"center-center\"},\"children\":[{\"type\":\"row\",\"children\":[{\"type\":\"column\",\"props\":{\"position_sticky_breakpoint\":\"m\",\"image_position\":\"center-center\",\"media_overlay_gradient\":\"\"},\"children\":[{\"type\":\"image\",\"props\":{\"margin\":\"small\",\"image_svg_color\":\"emphasis\",\"image\":\"wp-content\\\/uploads\\\/2021\\\/09\\\/Ayano-Shiba-e1647002528375.jpeg\",\"image_alt\":\"Image by Ayano Shiba\",\"image_width\":\"200\",\"image_border\":\"circle\",\"text_align\":\"center\",\"maxwidth\":\"medium\",\"block_align\":\"center\"},\"name\":\"\"},{\"type\":\"grid\",\"props\":{\"show_title\":true,\"show_meta\":true,\"show_content\":true,\"show_image\":true,\"show_link\":true,\"grid_default\":\"1\",\"grid_medium\":\"2\",\"filter_style\":\"tab\",\"filter_all\":true,\"filter_position\":\"top\",\"filter_align\":\"left\",\"filter_grid_width\":\"auto\",\"filter_grid_breakpoint\":\"m\",\"title_hover_style\":\"reset\",\"title_element\":\"h3\",\"title_align\":\"top\",\"title_grid_width\":\"1-2\",\"title_grid_breakpoint\":\"m\",\"meta_style\":\"meta\",\"meta_align\":\"below-title\",\"meta_element\":\"div\",\"content_column_breakpoint\":\"m\",\"icon_width\":80,\"image_align\":\"top\",\"image_grid_width\":\"1-2\",\"image_grid_breakpoint\":\"m\",\"image_svg_color\":\"emphasis\",\"link_text\":\"Read more\",\"link_style\":\"default\",\"margin\":\"default\",\"item_animation\":true},\"children\":[{\"type\":\"grid_item\",\"props\":{\"title\":\"About Ayano\",\"content\":\"\n\n<h6><strong>Workpackage <\\\/strong><\\\/h6>\\n\n\n<p>1.2<\\\/p>\\n\n\n<h6><strong>Position<\\\/strong><\\\/h6>\\n\n\n<p>PhD<\\\/p>\\n\n\n<h6><strong>Started<\\\/strong><\\\/h6>\\n\n\n<p>September 2021<\\\/p>\\n\n\n<h6><strong>Works at<\\\/strong><\\\/h6>\\n\n\n<p>Netherlands Institute for Neuroscience<\\\/p>\\n\n\n<h6><strong>Supervision Team<\\\/strong><\\\/h6>\\n\n\n<ul>\\n\n\n<li>Prof. Andries Kalsbeek<\\\/li>\\n\n\n<li>Dr. Chun-Xia Yi<\\\/li>\\n\n\n<li>Dr. Dirk-Jan Stenvers<\\\/li>\\n\n\n<li>Dr. Joram Mul<\\\/li>\\n<\\\/ul>\\n\n\n<h6><strong>Email<\\\/strong><\\\/h6>\\n\n\n<p><a href=\\\"a.shiba@nin.knaw.nl\\\">a.shiba@nin.knaw.nl<\\\/a><\\\/p>\\n\n\n<p><\\\/p>\",\"image\":\"\",\"image_alt\":\"Image by Ayano Shiba\"}},{\"type\":\"grid_item\",\"props\":{\"title\":\"Description of project\",\"content\":\"\n\n<p>My project aims to clarify how timed exercise impact on the metabolic system, and possibly develop the prevention and treatment for circadian disruption-triggered metabolic diseases; obesity and type 2 diabetes mellitus.<\\\/p>\\n\n\n<p>Currently we know that disturbance of the circadian clock triggered by shift work conditions are known to contribute to infertility, carcinogenesis and metabolic disorders. 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She wrote <a href=\\\"https:\\\/\\\/bioclockconsortium.org\\\/en\\\/news\\\/a-one-year-update-ayano-on-the-timing-of-exercise\\\/\\\">an update<\\\/a> on what she has done so far.<\\\/p>\",\"panel_style\":\"tile-muted\"}}]}]}]}]},{\"name\":\"Footer (EN)\",\"type\":\"section\",\"props\":{\"style\":\"secondary\",\"width\":\"\",\"vertical_align\":\"middle\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"title_breakpoint\":\"xl\",\"image_position\":\"center-center\",\"padding\":\"large\",\"padding_remove_bottom\":true,\"animation_delay\":false,\"preserve_color\":true,\"id\":\"footer\",\"class\":\"footer\"},\"children\":[{\"name\":\"\",\"type\":\"row\",\"props\":{\"layout\":\"1-2,1-2\",\"width\":\"xlarge\",\"margin\":\"xlarge\",\"vertical_align\":true,\"margin_remove_bottom\":false,\"column_gap\":\"large\",\"row_gap\":\"large\"},\"children\":[{\"name\":\"\",\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"text_color\":\"light\",\"width_medium\":\"1-2\",\"vertical_align\":\"middle\",\"media_overlay_gradient\":\"\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"name\":\"\",\"type\":\"headline\",\"props\":{\"title_element\":\"h2\",\"content\":\"KEEP UP TO DATE OF NEWS, NEW PROJECTS AND 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href=\\\"bioclock@lumc.nl\\\">bioclock@lumc.nl<\\\/a><\\\/p>\",\"maxwidth\":\"medium\",\"maxwidth_breakpoint\":\"m\",\"block_align\":\"center\"}}]},{\"name\":\"\",\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"style\":\"default\",\"width_medium\":\"1-4\",\"width_small\":\"1-2\",\"media_overlay_gradient\":\"\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"name\":\"\",\"type\":\"headline\",\"props\":{\"title_element\":\"h3\",\"content\":\"Follow 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href=\\\"https:\\\/\\\/twitter.com\\\/NWA_BioClock\\\">Twitter<\\\/a><\\\/p>\",\"link\":\"https:\\\/\\\/twitter.com\\\/\"}},{\"name\":\"\",\"type\":\"list_item\",\"props\":{\"content\":\"\n\n<p><a href=\\\"https:\\\/\\\/www.linkedin.com\\\/company\\\/bioclock\\\">LinkedIn<\\\/a><\\\/p>\",\"link\":\"https:\\\/\\\/www.instagram.com\\\/\"}}]}]}]}]},{\"type\":\"section\",\"props\":{\"style\":\"muted\",\"width\":\"xlarge\",\"vertical_align\":\"middle\",\"title_position\":\"top-left\",\"title_rotation\":\"left\",\"title_breakpoint\":\"xl\",\"image_position\":\"center-center\",\"padding\":\"xsmall\"},\"children\":[{\"type\":\"row\",\"props\":{\"layout\":\"1-5,4-5\",\"column_gap\":\"collapse\",\"row_gap\":\"collapse\"},\"children\":[{\"type\":\"column\",\"props\":{\"image_position\":\"center-center\",\"media_overlay_gradient\":\"\",\"width_medium\":\"1-5\",\"position_sticky_breakpoint\":\"m\"},\"children\":[{\"type\":\"image\",\"props\":{\"margin\":\"default\",\"image_svg_color\":\"emphasis\",\"image\":\"wp-content\\\/uploads\\\/2021\\\/03\\\/NWO-logo-witruimte.png\",\"image_alt\":\"NWO 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